Pointe Fentanyl Open Channel Reagent: A FDA approved, qualitative solution for testing Fentanyl and Norfentanyl

Fentanyl is

50 to 100 Times

More Potent

than morphine *

What are the Effects of Fentanyl:


  • Sedation
  • Confusion
  • Extreme Happiness
  • Problems Breathing
  • Nausea
  • Constipation
  • Unconsciouness *

Pointe Brand Fentanyl is the Superior Choice

Pointe Fentanyl Open Channel Reagent is FDA cleared and designed for prescription use on a number of automated clinical chemistry analyzers. The Pointe Fentanyl reagent is intended for the qualitative determination of norfentanyl in human urine at the cutoff value of 5 ng/mL. This is important because up to 85% of fentanyl is excreted over 3-4 days and only 26-55% of norfentanyl is excreted in that same time frame.

A Drug by Many Names...

Fentanyl is known as:
Prescription Names: Street Names:
Actiq® Apache
Duragesic® China White
Sublimaze® Jackpot *

A Drug Sold in Many Forms...

Illegal Fentanyl is sold as:
Powder Nasal Sprays
Dropped onto blotter paper Pills
Eye droppers *

Why Norfentanyl Testing Matters

  • Fentanyl is rapidly metabolized to its major inactive metabolite,
    norfentanyl **


  • Drugs that are rapidly metabolized (have a short half-life), such as fentanyl, are mainly detected indirectly by their metabolites. ***
    • Fentanyl’s half life is anywhere from 3-12 hours *****
    • Norfentanyl’s half life is 9-10 hours *****
  • Only immunoassays specifically directed toward the molecule will detect synthetic opioids, such as methadone or fentanyl ***
  • The most common reasons for opioid false-negative results are using incorrect testing for a specific opioid or there is insufficient concentration of opioid in the urine **

On the Rise ****


* https://www.drugabuse.gov/publications/drugfacts/fentanyl#ref
** Clinical Interpretation of Urine Drug Tests, Moeller, Karen E. et al., Mayo Clinic Proceedings, Volume 92, Issue 5, 774 – 796
*** https://www.remitigate.com/wp-content/uploads/2015/11/urine-Drug-Testing-in-Clinical-Practice-Ed6_2015-08.pdf
**** Data collected from Virginia Commonwealth University Health System (VCU Health) has collected a data set specifically from pain management compliance patients over the last three years (November 1, 2015 – October 31, 2018).
***** https://www.aruplab.com/files/resources/pain-management/DrugAnalytesPlasmaUrine.pdf

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