Pointe Buprenorphine Open Channel Reagent: A liquid, ready-to-use product

Buprenorphine’s maximal effects are

Less than opiods like

Heroin and Methadone,

which is perfect for opioid addiction treatment

What is Buprenorphine used for?

  Buprenorphine is an analgesic often used as a substitution treatment for heroin addiction or opiate dependence. At low doses, buprenorphine produces sufficient effects to enable opioid-addicted individuals to discontinue the misuse of opioids without experiencing withdrawal symptoms. For typical opioid-dependent patients who received a stable daily sublingual dose of 16 mg of buprenorphine and 4 mg of Naloxone for at least two weeks, 24-hour urinary elimination is approximately 11 % of daily dose. 

Pointe Brand Buprenorphine is the Superior Choice

The Pointe Buprenorphine Open Channel Reagent is intended for the qualitative and semi-quantitative determination of norbuprenorphine (a buprenorphine metabolite) in human urine at a cutoff value of 5 ng/mL and 10 ng/mL. The assay is designed for prescription use with a number of automated clinical chemistry analyzers.

Buprenorphine Screening At A Glance

Based on a study performed by Harvard Medical school and others, the sensitivity, specificity and percentage agreement of Pointe Buprenorphine (5ng/mL) and (10ng/mL), and CEDIA compared to LC/MS-MS for the 149 samples are presented in the table above. The Pointe Buprenorphine methodology provides highly specific and sensitive detection of buprenorphine use, without the potential for opioid cross-reactivity. The Pointe Buprenorphine using both cutoffs demonstrated 100% specificity for buprenorphine and its metabolites, and provided higher overall agreements.*

Why Buprenorphine Testing Matters


* *Melanson, Stacy & Snyder, Marion & Jarolim, Petr & Flood, James. (2012). A New Highly Specific Buprenorphine Immunoassay for Monitoring Buprenorphine Compliance and Abuse. Journal of analytical toxicology. 36. 201-6. 10.1093/jat/bks003. 

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