For the quantitative determination of C-reactive protein in serum or plasma by latex particle enhanced immunoturbidimetric assay using the Mindray BS-200 analyzer.
Latex particles coated with antibody specific to human CRP aggregate in the presence of CRP from the sample forming immune complexes. The immune complexes cause an increase in light scattering which is proportional to the concentration of CRP in the serum. The light scattering is measured by reading turbidity (absorbance) at 570 nm. The CRP concentration is determined from a calibration curve developed from CRP standards of known concentration.